Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.41 |
| ▸ | NPY4R | P50391 | 14/20 | 0.39 |
| ▸ | NPY1R | P25929 | 9/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.39 |
| ▸ | NPY2R | P49146 | 5/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22736777 | 0.87 | SIRT5 (0.46) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL19975767 | 0.85 | SIRT6 (0.48) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL1521358 | 0.84 | SIRT6 (0.43) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL19791333 | 0.83 | TFPI (0.41) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL19791191 | 0.83 | TFPI (0.41) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL17732656 | 0.83 | GNPAT (0.47) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL26653399 | 0.83 | SIRT6 (0.47) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL22334062 | 0.83 | SIRT6 (0.47) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL22106685 | 0.83 | SIRT6 (0.47) | SIRT6SIRT1SIRT5NPY4RNPY1R | |
| SCHEMBL22106686 | 0.83 | SIRT6 (0.46) | SIRT6SIRT1SIRT5NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272765-A1 | PEPTIDE DERIVATIVE FOR REGULATING THYMIC STROMAL LYMPHOID PROTEIN-MEDIATED SIGNALING AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ALLERGY AND ASTHMA DISEASES COMPRISING SAME | Korea University Research and Business Foundation, Sejong Campus (KR) | 2018-01-24 | — | — | EP | disclosed |