Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686278 | 0.86 | KDM1A (0.46) | KDM1AGPR119LMNAKMT2AMEN1 | |
| SCHEMBL15686279 | 0.84 | KDM1A (0.45) | KDM1AGPR119KMT2AMEN1AADAT | |
| SCHEMBL26090253 | 0.83 | KDM1A (0.59) | KDM1AGPR119KMT2AMEN1KDM4E | |
| SCHEMBL30346003 | 0.83 | KDM1A (0.59) | KDM1AGPR119KMT2AMEN1KDM4E | |
| SCHEMBL1985926 | 0.83 | KDM1A (0.59) | KDM1AGPR119KMT2AMEN1KDM4E | |
| Trifluoroacetic Acid SCHEMBL18783557 | 0.82 | KDM1A (0.43) | KDM1AGPR119KMT2AMEN1MAPT | |
| SCHEMBL19893422 | 0.79 | KDM1A (0.46) | KDM1ANPSR1KMT2AMEN1AADAT | |
| Hydrochloric Acid SCHEMBL20262215 | 0.78 | KDM1A (0.46) | KDM1ANPSR1KMT2AMEN1MAPT | |
| SCHEMBL22868107 | 0.77 | SMN1; SMN2 (0.45) | LMNANPSR1KMT2AMEN1MAPT | |
| SCHEMBL8399608 | 0.76 | GPR119 (0.43) | KDM1AGPR119LMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272749-A1 | AMINO-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | Bayer Pharma Aktiengesellschaft (DE) | 2018-01-24 | — | — | EP | disclosed |