Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878473 | 0.86 | ALDH1A1 (0.43) | GPR119KDM1AKMT2AMEN1EPHX2 | |
| SCHEMBL8878468 | 0.86 | ALDH1A1 (0.43) | GPR119KDM1AKMT2AMEN1EPHX2 | |
| SCHEMBL6650959 | 0.86 | ALDH1A1 (0.43) | GPR119KDM1AKMT2AMEN1EPHX2 | |
| SCHEMBL13091175 | 0.82 | NOTUM (0.48) | LMNAGAAALOX12SMN1; SMN2KMT2A | |
| SCHEMBL6649701 | 0.79 | ALDH1A1 (0.43) | GPR119KDM1AKMT2AMEN1EPHX2 | |
| SCHEMBL19791975 | 0.76 | KDM1A (0.47) | GPR119KDM1ALMNANPSR1KMT2A | |
| SCHEMBL3733255 | 0.74 | PDE4A (0.42) | GPR119KDM1ASMN1; SMN2MAPT | |
| SCHEMBL12341085 | 0.74 | PDE4A (0.42) | GPR119KDM1ASMN1; SMN2MAPT | |
| SCHEMBL23063860 | 0.73 | DRD2 (0.52) | GPR119KDM1ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL22868066 | 0.73 | KDM4E (0.41) | GPR119KDM1ALMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994544-A | PRODUCING A 5H-CHROMENO(3,4-F)QUINOLINE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-11-30 | — | — | US | disclosed |