Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886420 | 0.76 | RAB9A (0.39) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9316102 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2095052 | 0.73 | HPGD (0.43) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL153460 | 0.69 | NPC1 (0.42) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3026269 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5172196 | 0.67 | ALDH1A1 (0.43) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2359084 | 0.67 | NPC1 (0.40) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28858509 | 0.67 | NPC1 (0.41) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28858506 | 0.67 | NPC1 (0.41) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9494433 | 0.67 | HPGD (0.38) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107977-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |