Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487995 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL15590866 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL16487999 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL15590864 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL15590865 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| Bromide SCHEMBL16670293 | 0.98 | GNAI3 (0.46) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL15590758 | 0.92 | GNAI3 (0.37) | GNAI3GNAO1GNAI1KDM4ELMNA | |
| SCHEMBL15689958 | 0.90 | HRH3 (0.37) | GNAI3GNAO1GNAI1KCNH2 | |
| SCHEMBL15689947 | 0.90 | HRH3 (0.37) | GNAI3GNAO1GNAI1KCNH2 | |
| SCHEMBL15590867 | 0.90 | HRH3 (0.37) | GNAI3GNAO1GNAI1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272740-A2 | HIGH STABILITY DIIONIC LIQUID SALTS | Sigma-Aldrich Co. LLC (US) | 2018-01-24 | — | — | EP | disclosed |