Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979560 | 1.00 | ALDH1A1 (0.32) | ALDH1A1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1979536 | 1.00 | ALDH1A1 (0.32) | ALDH1A1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL18490871 | 0.82 | GABRP (0.43) | ALDH1A1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL4247232 | 0.82 | GABRP (0.43) | ALDH1A1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL29155903 | 0.80 | TSHR (0.37) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL29155901 | 0.80 | TSHR (0.37) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL29155900 | 0.79 | GABRR1 (0.32) | — | |
| SCHEMBL9601128 | 0.79 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL29155897 | 0.79 | GABRR1 (0.32) | — | |
| SCHEMBL13731404 | 0.78 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071716-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |