Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.67 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.67 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16606321 | 0.86 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL10028665 | 0.84 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL16924691 | 0.83 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL6132943 | 0.81 | CHRNB2 (0.73) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL6674571 | 0.80 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL31044635 | 0.80 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL30093157 | 0.80 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL185582 | 0.78 | PYCR1 (0.67) | PYCR1KDM4EALDH1A1LMNA | |
| SCHEMBL8348697 | 0.77 | CHRNB2 (0.73) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL21278464 | 0.77 | CHRNB2 (0.73) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015818-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-01-25 | — | — | WO | disclosed |