Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL802751 | 0.78 | — | — | |
| SCHEMBL13747439 | 0.78 | — | — | |
| SCHEMBL18755366 | 0.78 | — | — | |
| SCHEMBL17053355 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18755373 | 0.78 | — | — | |
| SCHEMBL14329784 | 0.78 | — | — | |
| SCHEMBL4355915 | 0.78 | GBA1 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8964398 | 0.76 | — | — | |
| SCHEMBL2627862 | 0.75 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL15926062 | 0.75 | GBA1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | ALDH1A1 2597/4885SMN1; SMN2 4144/4885TSHR 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.