Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840853 | 0.85 | HSD11B1 (0.44) | HSD11B1CYP3A4BCHEALDH1A1LMNA | |
| SCHEMBL15840875 | 0.84 | HSD11B1 (0.43) | HSD11B1CYP3A4BCHEALDH1A1 | |
| SCHEMBL19801319 | 0.80 | PRKDC (0.32) | — | |
| SCHEMBL19794366 | 0.79 | HSD11B1 (0.33) | HSD11B1CYP3A4LMNA | |
| SCHEMBL19794407 | 0.76 | PRKDC (0.33) | ALDH1A1 | |
| SCHEMBL15840869 | 0.76 | HSD11B1 (0.39) | HSD11B1CYP3A4BCHEALDH1A1LMNA | |
| SCHEMBL17298893 | 0.74 | HSD11B1 (0.44) | HSD11B1CYP3A4BCHEALDH1A1LMNA | |
| SCHEMBL15840882 | 0.74 | HSD11B1 (0.44) | HSD11B1CYP3A4BCHEALDH1A1LMNA | |
| SCHEMBL17298918 | 0.74 | HSD11B1 (0.46) | HSD11B1CYP3A4BCHEALDH1A1LMNA | |
| SCHEMBL19801317 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | HSD11B1 4284/4885CYP3A4 2173/4885BCHE 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.