Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19794515 | 0.97 | ALOX5 (0.45) | ALOX5MAPTALDH1A1KDM4EHDAC6 | |
| SCHEMBL19794476 | 0.90 | MAPT (0.41) | ALOX5MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL18015610 | 0.86 | ALOX5 (0.41) | ALOX5MAPTALDH1A1POLBNPSR1 | |
| SCHEMBL29292972 | 0.86 | MEN1 (0.38) | ALOX5MAPTALDH1A1KDM4EHDAC6 | |
| SCHEMBL22276558 | 0.85 | ALOX5 (0.41) | ALOX5MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL21304237 | 0.85 | ALOX5 (0.52) | ALOX5MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL22888668 | 0.85 | ALOX5 (0.49) | ALOX5MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL22888720 | 0.85 | ALOX5 (0.52) | ALOX5MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL22889030 | 0.85 | ALOX5 (0.52) | ALOX5MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL22889101 | 0.84 | ALOX5 (0.51) | ALOX5MAPTALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | ALOX5 3634/4885MAPT 2450/4885ALDH1A1 2742/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | ALOX5 4152/4885MAPT 639/4885ALDH1A1 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.