Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 9/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29411215 | 0.98 | TRPA1 (0.33) | TRPA1TRPV3ALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL20971485 | 0.98 | TRPA1 (0.33) | TRPA1TRPV3ALOX5APFEN1 | |
| SCHEMBL16635524 | 0.84 | TRPA1 (0.40) | TRPA1TRPV3ALOX5APFEN1 | |
| SCHEMBL29411263 | 0.84 | TRPA1 (0.38) | TRPA1TRPV3 | |
| SCHEMBL18018374 | 0.84 | TRPA1 (0.38) | TRPA1TRPV3 | |
| SCHEMBL16635018 | 0.83 | TRPA1 (0.40) | TRPA1TRPV3 | |
| SCHEMBL18018427 | 0.83 | TRPA1 (0.32) | TRPA1TRPV3 | |
| Hydrochloric Acid SCHEMBL17979196 | 0.83 | TRPA1 (0.38) | TRPA1TRPV3 | |
| SCHEMBL16635230 | 0.83 | TRPA1 (0.40) | TRPA1TRPV3 | |
| SCHEMBL18018444 | 0.82 | TRPV3 (0.32) | TRPA1TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487853-B1 | BICYCLIC PROLINE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-06-08 | — | — | EP | disclosed |
| WO-2018015410-A1 | BICYCLIC PROLINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-01-25 | — | — | WO | disclosed |