Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19795020 | 0.84 | TRPA1 (0.39) | TRPA1FGFR1 | |
| SCHEMBL17979259 | 0.81 | TRPA1 (0.48) | TRPA1FGFR1 | |
| SCHEMBL16647990 | 0.81 | TRPA1 (0.46) | TRPA1FGFR1 | |
| SCHEMBL17979414 | 0.81 | TRPA1 (0.46) | TRPA1FGFR1 | |
| Hydrochloric Acid SCHEMBL16635998 | 0.80 | TRPA1 (0.46) | TRPA1FGFR1 | |
| SCHEMBL19807603 | 0.77 | TRPA1 (0.55) | TRPA1FGFR1 | |
| SCHEMBL17979498 | 0.74 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL17979290 | 0.71 | TRPA1 (0.44) | TRPA1 | |
| SCHEMBL28847111 | 0.71 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL19795013 | 0.70 | TRPA1 (0.40) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015410-A1 | BICYCLIC PROLINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-01-25 | — | — | WO | disclosed |