Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.72 |
| ▸ | GABRP | O00591 | 2/20 | 0.62 |
| ▸ | GABRD | O14764 | 2/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.62 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.62 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.62 |
| ▸ | GABRE | P78334 | 2/20 | 0.62 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.62 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.62 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.62 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL9481361 | 0.89 | CCKBR (0.69) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9481172 | 0.87 | CCKBR (0.83) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10645219 | 0.87 | CCKBR (0.67) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2214365 | 0.85 | CCKBR (0.64) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30497898 | 0.85 | CCKBR (0.64) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9481365 | 0.84 | CCKBR (1.00) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2215023 | 0.83 | GABRP (0.65) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9483048 | 0.81 | CCKBR (1.00) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10646844 | 0.80 | GABRP (0.65) | CCKBRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1980188 | 0.80 | GSK3B (0.63) | CCKBRGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070298-A1 | DI-SUBSTITUTED 9H-PYRIDO[3,4-B]INDOLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |