Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073944 | 0.81 | UHRF1 (0.42) | SCN5AS1PR1 | |
| SCHEMBL20642466 | 0.78 | PGK1 (0.36) | SCN5A | |
| SCHEMBL23044965 | 0.78 | SCN5A (0.37) | SCN5AS1PR1 | |
| SCHEMBL30932094 | 0.78 | SCN5A (0.37) | SCN5AS1PR1 | |
| SCHEMBL12828162 | 0.75 | CYP3A4 (0.33) | SCN5A | |
| SCHEMBL13475570 | 0.73 | SCN5A (0.38) | SCN5AS1PR1 | |
| SCHEMBL30932101 | 0.70 | AR (0.40) | — | |
| SCHEMBL16707464 | 0.69 | SCN5A (0.36) | SCN5AS1PR1 | |
| SCHEMBL9133817 | 0.68 | — | — | |
| SCHEMBL12828166 | 0.68 | PDE2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015410-A1 | BICYCLIC PROLINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-01-25 | — | — | WO | disclosed |