Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932094 | 1.00 | SCN5A (0.37) | SCN5AS1PR1CYP1A2HRH4MBOAT4 | |
| SCHEMBL13073944 | 0.81 | UHRF1 (0.42) | SCN5AS1PR1CYP1A2 | |
| SCHEMBL19795270 | 0.78 | SCN5A (0.34) | SCN5AS1PR1 | |
| SCHEMBL20642466 | 0.78 | PGK1 (0.36) | SCN5ACYP1A2ANO1 | |
| SCHEMBL22759822 | 0.76 | NQO2 (0.41) | — | |
| SCHEMBL24510022 | 0.76 | ALOX5AP (0.33) | CYP1A2SCN9A | |
| SCHEMBL12828162 | 0.75 | CYP3A4 (0.33) | SCN5AHRH4 | |
| SCHEMBL31274754 | 0.73 | HPGD (0.39) | S1PR1 | |
| SCHEMBL19346801 | 0.73 | HPGD (0.39) | S1PR1 | |
| SCHEMBL17336545 | 0.73 | MAPT (0.46) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |