Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Agn-201904 SCHEMBL2245875 | 0.94 | CYP2C9 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Agn-201904 SCHEMBL29596867 | 0.94 | CYP2C9 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Agn-201904 SCHEMBL5764653 | 0.94 | CYP2C9 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Agn-201904 SCHEMBL5330690 | 0.94 | CYP2C9 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Agn-201904 SCHEMBL5764638 | 0.94 | CYP2C9 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12353545 | 0.92 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13053500 | 0.91 | ALDH1A1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5332714 | 0.90 | CYP2C9 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5763595 | 0.90 | CYP2C9 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5332710 | 0.90 | CYP2C9 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021319-A1 | COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021319-A1 | COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL INFECTIONS | FABP2, VIP, ALPI | PSEN1 3492/4885PSEN2 3613/4885APH1B 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.