Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19236805 | 0.83 | CFD (0.55) | — | |
| SCHEMBL19795252 | 0.80 | KMT2A (0.54) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL29339268 | 0.77 | HPGD (0.51) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL17785276 | 0.70 | RPS6KA1 (0.55) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL29781687 | 0.70 | CFD (0.62) | — | |
| SCHEMBL16421756 | 0.69 | HTR2A (0.51) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL19208371 | 0.68 | CFD (0.58) | — | |
| SCHEMBL19236856 | 0.68 | CFD (0.57) | — | |
| SCHEMBL19795692 | 0.68 | CFD (0.40) | POLB | |
| SCHEMBL21346105 | 0.68 | HTR2A (0.52) | ALDH1A1GAAROCK2ROCK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015818-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-01-25 | — | — | WO | disclosed |