Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19236805 | 0.82 | CFD (0.55) | — | |
| SCHEMBL19795647 | 0.80 | MEN1 (0.50) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL19444721 | 0.75 | RAB9A (0.61) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL2905302 | 0.75 | RIPK1 (0.62) | KMT2AMEN1SMN1; SMN2HPGDRIPK1 | |
| SCHEMBL30192682 | 0.75 | RIPK1 (0.62) | KMT2AMEN1SMN1; SMN2HPGDRIPK1 | |
| Hydrochloric Acid SCHEMBL30279534 | 0.73 | RIPK1 (0.60) | KMT2APTGER1MEN1SMN1; SMN2HPGD | |
| SCHEMBL14451968 | 0.73 | SLC6A2 (0.49) | KMT2AMEN1SMN1; SMN2RIPK1ALDH1A1 | |
| SCHEMBL5072892 | 0.72 | PKM (0.66) | KMT2AHPGDTDP1ALDH1A1LMNA | |
| SCHEMBL23134945 | 0.71 | HPGD (0.57) | KMT2AMEN1SMN1; SMN2HPGDRIPK1 | |
| SCHEMBL4038051 | 0.71 | HPGD (0.57) | KMT2AMEN1SMN1; SMN2HPGDRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015818-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-01-25 | — | — | WO | disclosed |