SCHEMBL1979656

SCHEMBL1979656

O=C(Nc1ccccc1)N1CCC(c2nc(C3=NOC(c4ccccc4)C3)cs2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27821648 0.88 FAAH (0.80) FAAH
SCHEMBL12611670 0.87 FAAH (0.78) FAAH
SCHEMBL23356538 0.87 FAAH (0.78) FAAH
SCHEMBL23356537 0.87 FAAH (0.78) FAAH
SCHEMBL3692928 0.86 FAAH (0.85) FAAH
SCHEMBL192218 0.86 FAAH (0.85) FAAH
SCHEMBL232667 0.84 FAAH (0.77) FAAH
SCHEMBL18673205 0.84 FAAH (0.74) FAAH
SCHEMBL1978094 0.84 FAAH (1.00) FAAH
SCHEMBL194610 0.83 FAAH (0.78) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130045948-A1 AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE E I DU PONT DE NEMOURS AND COMPANY (US) 2013-02-21 US disclosed
EP-2509978-A1 AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE E.I. Du Pont De Nemours And Company (US) 2012-10-17 EP disclosed
WO-2011072207-A1 AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045948-A1 AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, NCEH1 FAAH 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.