Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 8/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070539 | 0.93 | THRB (0.44) | THRBPTPN11PTPN1PTPN6CNR2 | |
| SCHEMBL19796744 | 0.91 | RARB (0.46) | THRBPTPN11PTPN1PTPN6CNR2 | |
| SCHEMBL19796752 | 0.89 | THRB (0.44) | THRBPTPN11PTPN1PTPN6CNR2 | |
| SCHEMBL19624613 | 0.89 | TSHR (0.38) | THRBPTPN11PTPN1PTPN6CNR2 | |
| SCHEMBL19796748 | 0.89 | THRB (0.51) | THRBPTPN11PTPN1PTPN6THRA | |
| SCHEMBL19796311 | 0.88 | TSHR (0.38) | THRBPTPN11PTPN1PTPN6CNR2 | |
| SCHEMBL19796403 | 0.88 | THRB (0.50) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL19796749 | 0.87 | RARB (0.47) | THRBPTPN11PTPN1PTPN6CNR2 | |
| SCHEMBL19804119 | 0.87 | THRB (0.46) | THRBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19796750 | 0.87 | RARB (0.46) | THRBPTPN11PTPN1PTPN6CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | SP1, C1S, AP3D1 | THRB 4323/4885PTPN11 2304/4885PTPN1 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.