Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19804119 | 0.90 | THRB (0.46) | TSHRMAPK1THRBESR1LMNA | |
| SCHEMBL17072446 | 0.89 | RARB (0.42) | TSHRL3MBTL1MAPK1THRBFFAR1 | |
| SCHEMBL19796763 | 0.89 | THRB (0.48) | TSHRTHRBALDH1A1RARARARB | |
| SCHEMBL19796311 | 0.86 | TSHR (0.38) | TSHRTHRBESR1LMNAALDH1A1 | |
| SCHEMBL19804162 | 0.83 | L3MBTL1 (0.43) | TSHRL3MBTL1MAPK1THRBFFAR1 | |
| SCHEMBL17070539 | 0.82 | THRB (0.44) | THRBRARARARBRARGCNR2 | |
| SCHEMBL19804246 | 0.82 | TSHR (0.41) | TSHRTHRBFFAR1FFAR4ALDH1A1 | |
| SCHEMBL19804594 | 0.81 | THRB (0.46) | TSHRL3MBTL1THRBFFAR1FFAR4 | |
| SCHEMBL20288603 | 0.81 | L3MBTL1 (0.36) | L3MBTL1MAPK1FFAR1FFAR4LMNA | |
| SCHEMBL19803976 | 0.80 | THRB (0.40) | TSHRTHRBFFAR1FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246305-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-11-22 | — | — | EP | disclosed |