Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19797126 | 0.95 | THRB (0.39) | THRBSPHK1PPARGPPARAFFAR4 | |
| SCHEMBL19796835 | 0.95 | SPHK1 (0.36) | THRBSPHK1PPARGPPARAFFAR4 | |
| SCHEMBL19797101 | 0.93 | THRB (0.37) | THRBSPHK1PPARGPPARAFFAR4 | |
| SCHEMBL19796899 | 0.91 | THRB (0.39) | THRBPPARGPPARAFFAR4HPGD | |
| SCHEMBL19797112 | 0.91 | SPHK1 (0.38) | THRBSPHK1FFAR4PTPN1PTPN6 | |
| SCHEMBL19796839 | 0.90 | SPHK1 (0.37) | THRBSPHK1PPARGPPARAFFAR4 | |
| SCHEMBL19796834 | 0.90 | THRB (0.36) | THRBSPHK1PPARGPPARAFFAR4 | |
| SCHEMBL19797102 | 0.89 | THRB (0.38) | THRBPPARGPPARAFFAR4HPGD | |
| SCHEMBL19796871 | 0.89 | SPHK1 (0.35) | SPHK1PPARGPPARAFFAR4TSHR | |
| SCHEMBL19796842 | 0.88 | RAB9A (0.38) | THRBPPARGPPARAFFAR4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | SP1, C1S, AP3D1 | THRB 4323/4885SPHK1 608/4885PPARG 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.