SCHEMBL19797282

SCHEMBL19797282

CC1(C)OB(c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2ccc4ccccc4c2-3)OC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.43
LIPG Q9Y5X9 7/20 0.43
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.33
DNMT1 P26358 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19822182 1.00 LPL (0.43) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL20225280 0.99 LPL (0.42) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL20225287 0.99 LPL (0.42) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL20225281 0.93 LPL (0.43) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL29761248 0.90 LPL (0.41) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL22289275 0.90 LPL (0.41) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL16219708 0.88 LPL (0.43) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL23930748 0.88 LPL (0.39) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL29761250 0.88 LPL (0.39) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL19869597 0.88 LPL (0.39) LPLLIPGPRMT5WDR77IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512841-B1 COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES MERCK PATENT GMBH (DE) 2023-04-26 EP disclosed
US-11447464-B2 Compounds with spirobifluorene-structures MERCK PATENT GMBH (DE) 2022-09-20 US disclosed
US-20190194164-A1 COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES MERCK PATENT GMBH (DE) 2019-06-27 US disclosed
US-10283716-B2 Compound for organic electric element, organic electric element using the same, and electronic device comprising same DUK SAN NEOLUX CO., LTD. (KR) 2019-05-07 US disclosed
US-20180026187-A1 NOVEL COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026187-A1 NOVEL COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD. (KR) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180026187-A1 NOVEL COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE COMPRISING SAME EBPL, OR51E2, EML4 LPL 2506/4885LIPG 1659/4885PRMT5 3888/4885
US-11447464-B2 Compounds with spirobifluorene-structures SLCO1B3, SLCO4C1, SLCO1B1 LPL 4408/4885LIPG 3966/4885PRMT5 4276/4885
US-10283716-B2 Compound for organic electric element, organic electric element using the same, and electronic device comprising same EBPL, OR51E2, EML4 LPL 2503/4885LIPG 1730/4885PRMT5 3754/4885
US-20190194164-A1 COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES SLCO1B3, SLCO4C1, SLCO1B1 LPL 4408/4885LIPG 3966/4885PRMT5 4276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.