Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494352 | 0.95 | MEN1 (0.40) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL14029172 | 0.94 | CES2 (0.43) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL15494366 | 0.88 | ALDH1A1 (0.38) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL14744144 | 0.87 | MEN1 (0.46) | MEN1KMT2AMAPTCYP2C19CYP1A2 | |
| SCHEMBL14744143 | 0.87 | MEN1 (0.46) | MEN1KMT2AMAPTCYP2C19CYP1A2 | |
| SCHEMBL18385889 | 0.84 | SLC22A2 (0.44) | MEN1KMT2AMAPTCYP2C19CYP1A2 | |
| SCHEMBL5001311 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL5001309 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL15306805 | 0.81 | CES2 (0.54) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL12593268 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2AMAPTCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578265-B2 | AIEgens for cancer cell imaging | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-02-14 | — | — | US | disclosed |
| US-20210371735-A1 | AIEgens for Cancer Cell Imaging | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-12-02 | — | — | US | disclosed |
| WO-2018014865-A1 | AIEGENS FOR CANCER CELL IMAGING | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578265-B2 | AIEgens for cancer cell imaging | CD4, MKI67, CCNB1 | MEN1 308/4885KMT2A 3649/4885MAPT 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.