Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17999343 | 0.92 | ACHE (0.35) | ALDH1A1POLBACHEL3MBTL1OPRM1 | |
| SCHEMBL17999563 | 0.92 | ACHE (0.35) | ALDH1A1POLBACHEL3MBTL1OPRM1 | |
| SCHEMBL17999282 | 0.92 | ACHE (0.35) | ALDH1A1POLBACHEL3MBTL1OPRM1 | |
| SCHEMBL3017592 | 0.73 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1OPRM1KMT2AMEN1 | |
| SCHEMBL17999372 | 0.71 | ALDH1A1 (0.43) | ALDH1A1POLBACHEL3MBTL1KMT2A | |
| SCHEMBL17999374 | 0.71 | ALDH1A1 (0.43) | ALDH1A1POLBACHEL3MBTL1KMT2A | |
| SCHEMBL17553914 | 0.68 | HSD17B10 (0.49) | ALDH1A1HSD17B10TP53KMT2AMEN1 | |
| SCHEMBL17999367 | 0.68 | F9 (0.47) | L3MBTL1HSD11B1KMT2AMEN1LMNA | |
| SCHEMBL17999264 | 0.67 | F9 (0.39) | — | |
| SCHEMBL17999385 | 0.67 | F9 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022747-A1 | Factor IXa Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022747-A1 | Factor IXa Inhibitors | F9, TFPI, F12 | ALDH1A1 672/4885POLB 3869/4885ACHE 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.