Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21019972 | 0.91 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1LMNAPOLBHTT | |
| SCHEMBL21019724 | 0.89 | RARB (0.32) | — | |
| SCHEMBL19799092 | 0.89 | PTPN1 (0.33) | ALDH1A1 | |
| SCHEMBL21241720 | 0.86 | PTPN1 (0.37) | SMN1; SMN2ALDH1A1LMNAPOLBHTT | |
| SCHEMBL20176728 | 0.86 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1LMNAPOLBHTT | |
| SCHEMBL19798700 | 0.86 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL19798703 | 0.86 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL18217156 | 0.85 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1LMNAPOLBHTT | |
| SCHEMBL19798352 | 0.85 | RARB (0.30) | — | |
| SCHEMBL16546613 | 0.85 | KDM4E (0.40) | SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168257-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| EP-3487955-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-05-20 | — | — | EP | disclosed |
| US-20190153320-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-05-23 | — | — | US | disclosed |
| WO-2018015320-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | WO | disclosed |