Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19737689 | 0.81 | KDM4E (0.40) | LMNAAOC3KDM4EALDH1A1HPGD | |
| SCHEMBL18596502 | 0.81 | KDM4E (0.40) | LMNAAOC3KDM4EALDH1A1HPGD | |
| SCHEMBL6558978 | 0.80 | LMNA (0.41) | LMNAAOC3KDM4EADRA2CADRA2A | |
| SCHEMBL366712 | 0.78 | LMNA (0.52) | LMNAAOC3KDM4EADRA2CADRA2A | |
| SCHEMBL3092744 | 0.78 | TAAR1 (0.41) | LMNAAOC3KDM4EADRA2AALDH1A1 | |
| SCHEMBL13676858 | 0.78 | TACR1 (0.46) | LMNAKDM4EADRA2AALDH1A1TSHR | |
| SCHEMBL873109 | 0.78 | KDM4E (0.44) | LMNAKDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL19506441 | 0.77 | KDM4E (0.37) | LMNAAOC3KDM4EADRA2CADRA2A | |
| SCHEMBL14945475 | 0.76 | GSR (0.47) | LMNAAOC3KDM4EALDH1A1TSHR | |
| SCHEMBL14945472 | 0.76 | GSR (0.47) | LMNAAOC3KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021467-A1 | METHOD OF BLOCKING PERCEPTION OF MALODOR | MONELL CHEMICAL SENSES CENTRE (US) | 2018-01-25 | — | — | US | disclosed |