Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426438 | 0.80 | HTR2B (0.36) | ALDH1A1MAPTTP53 | |
| SCHEMBL29294775 | 0.78 | PLA2G7 (0.64) | PLA2G7POLBKMT2AHSD11B1CYP2A6 | |
| SCHEMBL3410795 | 0.77 | PLA2G7 (0.37) | PLA2G7POLBKMT2AHSD11B1CYP2A6 | |
| SCHEMBL2944478 | 0.75 | ESR2 (0.42) | POLBKMT2ACYP2A6ALDH1A1RAB9A | |
| SCHEMBL5993767 | 0.73 | PTGDR2 (0.41) | KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10506631 | 0.72 | PLA2G7 (0.44) | PLA2G7POLBKMT2AHSD11B1CYP2A6 | |
| SCHEMBL7463096 | 0.72 | CYP2A6 (0.43) | KMT2AHSD11B1CYP2A6ALDH1A1NPC1 | |
| SCHEMBL458016 | 0.72 | CYP2A6 (0.48) | PLA2G7POLBKMT2AHSD11B1CYP2A6 | |
| SCHEMBL15354397 | 0.71 | PLA2G7 (0.67) | PLA2G7POLBKMT2AHSD11B1CYP2A6 | |
| SCHEMBL277914 | 0.71 | PLA2G7 (0.67) | PLA2G7POLBKMT2AHSD11B1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |