Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980000 | 0.77 | PLA2G7 (0.51) | PLA2G7POLBKMT2AHSD11B1TP53 | |
| SCHEMBL3410793 | 0.73 | PLA2G7 (0.37) | PLA2G7POLBKMT2AHTR1AHTR7 | |
| SCHEMBL15063673 | 0.69 | NOTUM (0.34) | — | |
| SCHEMBL15064001 | 0.65 | NOTUM (0.31) | — | |
| SCHEMBL458016 | 0.65 | CYP2A6 (0.48) | PLA2G7POLBKMT2AHSD11B1TP53 | |
| SCHEMBL7463096 | 0.65 | CYP2A6 (0.43) | KMT2AHSD11B1TP53CYP2A6ALDH1A1 | |
| SCHEMBL6852286 | 0.64 | KMT2A (0.43) | PLA2G7POLBKMT2AHSD11B1TP53 | |
| SCHEMBL1897406 | 0.64 | TP53 (0.57) | TP53RECQLLMNA | |
| SCHEMBL1979999 | 0.64 | PLA2G7 (0.43) | PLA2G7POLBKMT2AHSD11B1TP53 | |
| SCHEMBL15636889 | 0.64 | CYP2A6 (0.47) | PLA2G7POLBKMT2AHSD11B1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260032-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009094445-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |