Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19804627 | 0.90 | EGFR (0.45) | EGFRSLC6A9CYP11B1CYP11B2PDE4A | |
| SCHEMBL19804611 | 0.88 | EGFR (0.46) | EGFRSLC6A9CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL19804606 | 0.87 | SLC6A9 (0.40) | EGFRSLC6A9CYP11B1CYP11B2PDE4A | |
| SCHEMBL19796866 | 0.87 | THRB (0.42) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL19804192 | 0.86 | FEN1 (0.41) | EGFRCYP11B1CYP11B2PDE4AALDH1A1 | |
| SCHEMBL19804171 | 0.86 | FFAR4 (0.42) | CYP11B1CYP11B2KDM4ESMN1; SMN2POLB | |
| SCHEMBL19801965 | 0.86 | EGFR (0.47) | EGFRSLC6A9HTTBAZ2BBAZ2A | |
| SCHEMBL19796420 | 0.85 | THRB (0.38) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL19804617 | 0.85 | EGFR (0.38) | EGFRSLC6A9ALDH1A1POLBAPEX1 | |
| SCHEMBL19801688 | 0.85 | EGFR (0.38) | EGFRSLC6A9ALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | SP1, C1S, AP3D1 | EGFR 3426/4885SLC6A9 2938/4885CYP11B1 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.