SCHEMBL19804338

SCHEMBL19804338

C=CC(=O)OCc1cc(-c2ccc(CO)cc2)ccc1C

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.41
ERN1 O75460 2/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
THRB P10828 3/20 0.35
HDAC2 Q92769 1/20 0.35
AXL P30530 1/20 0.34
MERTK Q12866 1/20 0.34
CHEK1 O14757 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
ALOX5 P09917 1/20 0.33
ABL1 P00519 1/20 0.33
IKBKB O14920 1/20 0.33
CHUK O15111 1/20 0.33
HSD17B1 P14061 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19624374 0.91 CYP4F2 (0.40) PTGER4MTNR1AMTNR1BTHRBTSHR
SCHEMBL19624542 0.86 FFAR4 (0.43) PTGER4ERN1MTNR1AMTNR1BTHRB
SCHEMBL19804229 0.83 THRB (0.41) MTNR1AMTNR1BTHRBALOX5
SCHEMBL19796472 0.83 THRB (0.45) PTGER4ERN1MTNR1AMTNR1BTHRB
SCHEMBL19804224 0.83 PTGER4 (0.40) PTGER4ERN1MTNR1AMTNR1BHDAC2
SCHEMBL19804679 0.82 FFAR1 (0.41) PTGER4THRBTSHR
SCHEMBL19624475 0.82 MEN1 (0.41) PTGER4ERN1MTNR1AMTNR1BHDAC2
SCHEMBL19803980 0.81 MCL1 (0.34) PTGER4THRBTSHRHSD17B1
SCHEMBL19804209 0.80 FFAR4 (0.42) PTGER4ERN1THRBMEN1KMT2A
SCHEMBL19804167 0.80 ERN1 (0.38) ERN1THRBAXLMERTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, C1S, AP3D1 PTGER4 2215/4885ERN1 1080/4885MTNR1A 4362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.