Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | CCNC | P24863 | 5/20 | 0.35 |
| ▸ | CDK8 | P49336 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19804341 | 0.92 | PTGS1 (0.36) | AKR1C3AKR1C2ALOX5APFEN1BDKRB1 | |
| SCHEMBL19804049 | 0.91 | PTGS1 (0.37) | AKR1C3AKR1C2ALOX5APFEN1CA1 | |
| SCHEMBL19624666 | 0.88 | RARB (0.42) | AKR1C3AKR1C2RARARARBRARG | |
| SCHEMBL19804449 | 0.88 | PTGS1 (0.36) | AKR1C3AKR1C2ALOX5APFEN1CA1 | |
| SCHEMBL19804832 | 0.88 | MTNR1A (0.39) | CCNCCDK8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19804120 | 0.85 | CA2 (0.35) | AKR1C3AKR1C2CA1CA2RARB | |
| SCHEMBL19804040 | 0.85 | PTGS1 (0.37) | AKR1C3AKR1C2ALOX5APFEN1BDKRB1 | |
| SCHEMBL19804380 | 0.85 | PTGS1 (0.38) | AKR1C3AKR1C2ALOX5APFEN1 | |
| SCHEMBL19804378 | 0.84 | PTGS1 (0.36) | AKR1C3AKR1C2ALOX5APFEN1BDKRB1 | |
| SCHEMBL19007865 | 0.84 | RARB (0.47) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180023001-A1 | COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | SP1, C1S, AP3D1 | AKR1C3 1789/4885AKR1C2 3097/4885CCNC 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.