SCHEMBL19804591

SCHEMBL19804591

C=C(C)C(=O)OCc1cc2cc(-c3ccc(-c4ccccc4COC(=O)C(=C)C)cc3)ccc2cc1OCCO

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 3/20 0.36
PTGER4 P35408 3/20 0.35
PTGER3 P43115 3/20 0.35
PTGER1 P34995 2/20 0.35
PTGER2 P43116 2/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
FFAR4 Q5NUL3 10/20 0.34
FFAR1 O14842 9/20 0.34
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
RARG P13631 1/20 0.34
MCL1 Q07820 1/20 0.33
FABP7 O15540 1/20 0.33
FABP3 P05413 1/20 0.33
FABP5 Q01469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19624483 0.88 KDM4E (0.34) PTGER4PTGER3PTGER1PTGER2FFAR4
SCHEMBL19804602 0.88 EGFR (0.35) SLC6A9PTGER4PTGER3PTGER1PTGER2
SCHEMBL19797155 0.82 PTPN11 (0.34) FFAR4RARARARBRARG
SCHEMBL19804500 0.80 SLC6A9 (0.45) SLC6A9RARARARBRARG
SCHEMBL19797154 0.80 RARB (0.34) RARARARBRARG
SCHEMBL19804366 0.78 RARB (0.45) SLC6A9RARARARBRARGMCL1
SCHEMBL19804806 0.78 RARA (0.37) SLC6A9MTNR1AMTNR1BFFAR4FFAR1
SCHEMBL19804711 0.78 PTGER1 (0.44) PTGER4PTGER3PTGER1PTGER2FFAR4
SCHEMBL19804476 0.78 RARB (0.41) SLC6A9RARARARBRARGMCL1
SCHEMBL19804604 0.78 POLB (0.44) PTGER4PTGER3FFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, C1S, AP3D1 SLC6A9 2938/4885PTGER4 2215/4885PTGER3 3498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.