SCHEMBL1980540

SCHEMBL1980540

c1ccc(N(c2ccccc2)c2ccc(N(c3ccc4c(c3)c3ccccc3n4-c3ccccc3)c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SIGMAR1 Q99720 5/20 0.35
DHFR P00374 1/20 0.32
MAPK8 P45983 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
PTGER4 P35408 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
PER2 O15055 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
CRY1 Q16526 1/20 0.31
CRY2 Q49AN0 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12559394 1.00 KDM4E (0.46) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL1981141 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL12242937 0.97 KDM4E (0.49) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL12559428 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL29373277 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL4398134 0.96 KDM4E (0.47) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL29371762 0.96 KDM4E (0.50) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL13557391 0.96 L3MBTL1 (0.42) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL260981 0.96 KDM4E (0.50) KDM4EATML3MBTL1SIGMAR1DHFR
SCHEMBL10087130 0.96 KDM4E (0.50) KDM4EATML3MBTL1SIGMAR1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1805140-B1 CARBAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2016-08-31 EP disclosed
EP-1805140-B1 CARBAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2016-08-31 EP disclosed
US-9142783-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-22 US disclosed
US-9142783-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-22 US disclosed
US-9142783-B2 Light emitting element and light emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-22 US disclosed
US-8900728-B2 Carbazole derivative, and light emitting element and light emitting device using the carbazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-8900728-B2 Carbazole derivative, and light emitting element and light emitting device using the carbazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-8900728-B2 Carbazole derivative, and light emitting element and light emitting device using the carbazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-20130228765-A1 CARBAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-05 US disclosed
US-20130228765-A1 CARBAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-05 US disclosed
US-20080284328-A1 Carbazole Derivative, and Light Emitting Element and Light Emitting Device Using the Carbazole Derivative SEMICONDUCTOR ENERGY LABORATORY, LTD. (JP) 2008-11-20 US disclosed
US-20080284328-A1 Carbazole Derivative, and Light Emitting Element and Light Emitting Device Using the Carbazole Derivative SEMICONDUCTOR ENERGY LABORATORY, LTD. (JP) 2008-11-20 US disclosed
EP-1805140-A1 CARBAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-07-11 EP disclosed
WO-2007020804-A1 ARYLAMINE COMPOUND AND SYNTHETIC METHOD THEREOF SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-22 WO disclosed
WO-2007020804-A1 ARYLAMINE COMPOUND AND SYNTHETIC METHOD THEREOF SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-22 WO disclosed
US-20070037011-A1 Arylamine compound and synthetic method thereof SEMICONDUCTOR ENERGY LABORATORY CO. (JP) 2007-02-15 US disclosed
US-20070037011-A1 Arylamine compound and synthetic method thereof SEMICONDUCTOR ENERGY LABORATORY CO. (JP) 2007-02-15 US disclosed
US-20070037011-A1 Arylamine compound and synthetic method thereof SEMICONDUCTOR ENERGY LABORATORY CO. (JP) 2007-02-15 US disclosed
WO-2006059745-A1 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-06-08 WO disclosed
WO-2006043647-A1 CARBAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037011-A1 Arylamine compound and synthetic method thereof AHR, CYP2A13, ARNT KDM4E 1083/4885ATM 1463/4885L3MBTL1 3507/4885
US-20080284328-A1 Carbazole Derivative, and Light Emitting Element and Light Emitting Device Using the Carbazole Derivative CYP3A5, CYP2C19, CYP3A4 KDM4E 2507/4885ATM 4624/4885L3MBTL1 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.