Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12560105 | 0.76 | SLC9A1 (0.50) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL8445272 | 0.74 | SLC9A1 (0.48) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL29490311 | 0.74 | SLC9A1 (0.48) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL22862868 | 0.74 | KEAP1 (0.48) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL282111 | 0.74 | SLC9A1 (0.48) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL29975783 | 0.74 | SLC9A1 (0.48) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL8828592 | 0.73 | SLC9A1 (0.47) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL27661677 | 0.72 | KEAP1 (0.46) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL10130169 | 0.72 | KEAP1 (0.46) | SLC9A1KEAP1HPGDALDH1A1HSD17B10 | |
| SCHEMBL8771320 | 0.72 | SLC9A1 (0.46) | SLC9A1KEAP1HPGDMAPTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |