Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 7/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718764 | 0.88 | MEN1 (0.49) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL19805930 | 0.88 | SDHB (0.57) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL20985669 | 0.86 | KDM4E (0.61) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL5592977 | 0.85 | ALDH1A1 (0.64) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL19805780 | 0.84 | KDM4E (0.66) | KDM4ETP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL22912197 | 0.84 | MEN1 (0.49) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL20985691 | 0.82 | MEN1 (0.45) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL19805931 | 0.82 | MEN1 (0.45) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL20985731 | 0.81 | MEN1 (0.63) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL1257981 | 0.80 | MAPT (0.53) | KDM4ETP53L3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |