Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 19/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912204 | 0.94 | SDHB (0.74) | SDHB | |
| SCHEMBL19805963 | 0.90 | SDHB (0.73) | SDHBKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL22912211 | 0.89 | SDHB (0.60) | SDHB | |
| SCHEMBL29976286 | 0.85 | SDHB (1.00) | SDHB | |
| SCHEMBL19805875 | 0.85 | SDHB (1.00) | SDHB | |
| SCHEMBL19805897 | 0.85 | SDHB (0.70) | SDHB | |
| SCHEMBL29976686 | 0.84 | SDHB (0.72) | SDHB | |
| SCHEMBL19805854 | 0.84 | SDHB (0.72) | SDHB | |
| SCHEMBL19806079 | 0.84 | SDHB (0.57) | SDHB | |
| SCHEMBL19805838 | 0.84 | SDHB (0.72) | SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |