Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 17/20 | 0.72 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805897 | 0.91 | SDHB (0.70) | SDHBMKNK1MKNK2 | |
| SCHEMBL19806079 | 0.89 | SDHB (0.57) | SDHBMKNK1MKNK2 | |
| SCHEMBL22912298 | 0.87 | SDHB (0.64) | SDHB | |
| SCHEMBL19805963 | 0.87 | SDHB (0.73) | SDHB | |
| SCHEMBL19806064 | 0.86 | SDHB (0.73) | SDHB | |
| SCHEMBL19805970 | 0.85 | SDHB (0.57) | SDHB | |
| SCHEMBL22912204 | 0.85 | SDHB (0.74) | SDHB | |
| SCHEMBL19805776 | 0.85 | SDHB (0.58) | SDHBMKNK1MKNK2 | |
| SCHEMBL19806061 | 0.84 | SDHB (0.74) | SDHB | |
| SCHEMBL19805856 | 0.84 | SDHB (1.00) | SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |