Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 14/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805988 | 0.96 | SDHB (0.53) | SDHBTP53MAPTPDE2APDE3A | |
| SCHEMBL22912277 | 0.90 | SDHB (0.48) | SDHBTP53MAPTPDE2APDE3A | |
| SCHEMBL22912209 | 0.88 | SDHB (0.48) | SDHBTP53 | |
| SCHEMBL19805843 | 0.88 | SDHB (0.55) | SDHBTP53MAPTPDE2APDE3A | |
| SCHEMBL19805996 | 0.88 | SDHB (0.46) | SDHBTP53MAPTPDE2APDE3A | |
| SCHEMBL22912217 | 0.86 | SDHB (0.69) | SDHBTP53MAPT | |
| SCHEMBL19805828 | 0.84 | SDHB (0.70) | SDHBTP53MAPT | |
| SCHEMBL22912222 | 0.83 | SDHB (0.71) | SDHBTP53MAPT | |
| SCHEMBL22912212 | 0.82 | SDHB (0.46) | SDHBTP53MAPTPDE2APDE3A | |
| SCHEMBL26313143 | 0.82 | SDHB (0.57) | SDHBTP53MAPTPDE2APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |