Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 9/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806088 | 0.88 | SDHB (0.54) | SDHBTP53 | |
| SCHEMBL19805988 | 0.86 | SDHB (0.53) | SDHBKDM4ELMNATP53MAPK1 | |
| SCHEMBL20985651 | 0.86 | SDHB (0.64) | SDHBEPHX2KDM4ELMNATP53 | |
| SCHEMBL29976232 | 0.85 | SDHB (0.47) | SDHBEPHX2TP53 | |
| SCHEMBL20985704 | 0.85 | SDHB (0.47) | SDHBEPHX2TP53 | |
| SCHEMBL19805923 | 0.84 | SDHB (0.47) | SDHBKDM4EUSP2LMNATP53 | |
| SCHEMBL22912277 | 0.83 | SDHB (0.48) | SDHBTP53 | |
| SCHEMBL19805843 | 0.79 | SDHB (0.55) | SDHBLMNATP53 | |
| SCHEMBL19805996 | 0.79 | SDHB (0.46) | SDHBTP53 | |
| SCHEMBL22912222 | 0.78 | SDHB (0.71) | SDHBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |