Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806351 | 0.87 | POLB (0.41) | POLBDDR1S1PR1PPARGNCOA2 | |
| SCHEMBL29475164 | 0.86 | POLB (0.42) | POLB | |
| SCHEMBL19806340 | 0.86 | POLB (0.42) | POLB | |
| SCHEMBL25106818 | 0.83 | POLB (0.43) | POLBGRIN1GRIN2BDDR1S1PR1 | |
| SCHEMBL18819868 | 0.83 | POLB (0.43) | POLBGRIN1GRIN2BDDR1S1PR1 | |
| SCHEMBL18819841 | 0.83 | POLB (0.43) | POLBGRIN1GRIN2BDDR1LMNA | |
| SCHEMBL25106704 | 0.82 | POLB (0.42) | POLBGRIN1GRIN2BDDR1S1PR1 | |
| SCHEMBL18819840 | 0.81 | POLB (0.41) | POLBGRIN1GRIN2B | |
| SCHEMBL25106702 | 0.81 | POLB (0.41) | POLBLMNAHTTNPSR1 | |
| SCHEMBL19806349 | 0.81 | KCNH2 (0.34) | S1PR1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487860-B1 | CONDENSED BICYCLIC HETEROCYCLIC DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-18 | — | — | US | disclosed |
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-08 | — | — | US | disclosed |
| WO-2018015289-A1 | CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190239510-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, ACHE, BCHE | POLB 4096/4885ADORA2B 274/4885GRIN1 611/4885 |
| US-10561145-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, ACHE, BCHE | POLB 4096/4885ADORA2B 274/4885GRIN1 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.