Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753399 | 1.00 | RAB9A (0.58) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL1081956 | 1.00 | RAB9A (0.58) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL13359933 | 0.84 | RAB9A (0.58) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL9031830 | 0.83 | MAPT (0.56) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL3529276 | 0.82 | KDM4E (0.59) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL3529280 | 0.82 | KDM4E (0.59) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL3530470 | 0.82 | KDM4E (0.59) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL27494494 | 0.80 | KDM4E (0.57) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL5099857 | 0.78 | RAB9A (0.56) | RAB9ANPC1MAPTKDM4ELMNA | |
| SCHEMBL27560798 | 0.77 | NPC1 (0.58) | RAB9ANPC1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144154-A1 | Salts of 2-Substituted Quinolines | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2011-06-16 | — | — | US | claimed |
| US-8344145-B2 | Salts of 2-substituted quinolines | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2013-01-01 | — | — | US | disclosed |
| US-20110144154-A1 | Salts of 2-Substituted Quinolines | INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144154-A1 | Salts of 2-Substituted Quinolines | NQO2, SULT2A1, QTRT2 | RAB9A 921/4885NPC1 903/4885MAPT 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.