⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24221670 | 0.75 | — | — | |
| SCHEMBL19362483 | 0.73 | — | — | |
| SCHEMBL19362333 | 0.63 | — | — | |
| SCHEMBL16383563 | 0.62 | — | — | |
| SCHEMBL10183523 | 0.60 | — | — | |
| SCHEMBL22355813 | 0.59 | PTGS1 (0.40) | — | |
| SCHEMBL12566026 | 0.58 | PRKDC (0.33) | — | |
| SCHEMBL19214002 | 0.57 | PTGS1 (0.30) | — | |
| SCHEMBL12684250 | 0.57 | KDM4E (0.38) | — | |
| SCHEMBL18896365 | 0.56 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489219-B1 | THERAPEUTIC AGENT FOR GLAUCOMA | TOA EIYO LTD (JP) | 2020-12-16 | — | — | EP | disclosed |
| EP-3489219-A1 | THERAPEUTIC AGENT FOR GLAUCOMA | TOA Eiyo Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |
| WO-2018016611-A1 | THERAPEUTIC AGENT FOR GLAUCOMA | トーアエイヨー株式会社 | 2018-01-25 | — | — | WO | disclosed |