Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384162 | 0.94 | ITGB1 (0.39) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22756228 | 0.93 | ITGB3 (0.40) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL19544621 | 0.92 | ITGB3 (0.41) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL20900635 | 0.91 | PLG (0.41) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22756166 | 0.91 | ITGB1 (0.38) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL16306067 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22756182 | 0.90 | ITGB3 (0.40) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL16305985 | 0.89 | ITGB1 (0.42) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL16305707 | 0.89 | ITGB1 (0.42) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL16305709 | 0.89 | ITGB1 (0.42) | ITGB1ITGA4ITGB3ITGA2BPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ITGB1 3589/4885ITGA4 4651/4885ITGB3 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.