Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384162 | 0.93 | ITGB1 (0.39) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22756228 | 0.92 | ITGB3 (0.40) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL19544621 | 0.91 | ITGB3 (0.41) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL19807126 | 0.91 | ITGB1 (0.40) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL15037406 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22449334 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22756182 | 0.90 | ITGB3 (0.40) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL20900635 | 0.89 | PLG (0.41) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22756185 | 0.88 | KLKB1 (0.39) | ITGB1ITGA4ITGB3ITGA2BPLG | |
| SCHEMBL22384275 | 0.88 | PLG (0.47) | ITGB1ITGA4ITGB3ITGA2BPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |