Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.69 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | CDC25B | P30305 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.52 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.52 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 13/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798280 | 0.85 | PIM1 (0.61) | PIM1AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL25139348 | 0.80 | PIM1 (0.55) | PIM1AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL19798278 | 0.77 | PIM1 (0.73) | PIM1AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL16236717 | 0.76 | ELANE (0.41) | PIM1ELANECHEK1ALDH1A1CYP3A4 | |
| SCHEMBL17265615 | 0.75 | PIM1 (0.66) | PIM1AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL9006566 | 0.73 | PIM1 (0.63) | PIM1AURKACDC25BAURKBCYP1A1 | |
| SCHEMBL417088 | 0.73 | MAPT (0.48) | ELANECHEK1LMNAMEN1MAPT | |
| SCHEMBL21281775 | 0.73 | ELANE (0.47) | ELANECHEK1ALDH1A1CYP3A4LMNA | |
| Naphthazalin SCHEMBL149279 | 0.72 | TXNRD1 (1.00) | PIM1AURKACDC25BAURKBCYP1A1 | |
| Naphthazalin SCHEMBL29353283 | 0.72 | TXNRD1 (1.00) | PIM1AURKACDC25BAURKBCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180024435-A1 | RESIST COMPOSITION AND PATTERNING PROCESS USING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-01-25 | — | — | US | disclosed |