Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.63 |
| ▸ | AURKA | O14965 | 2/20 | 0.55 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006594 | 0.91 | PIM1 (0.49) | PIM1AURKACDC25BAURKBTXNRD1 | |
| SCHEMBL9006672 | 0.75 | TOP1 (0.59) | PIM1AURKACDC25BAURKBTXNRD1 | |
| SCHEMBL17265615 | 0.74 | PIM1 (0.66) | PIM1AURKACDC25BAURKBTXNRD1 | |
| Naphthazalin SCHEMBL29353283 | 0.74 | TXNRD1 (1.00) | PIM1AURKACDC25BAURKBTXNRD1 | |
| Naphthazalin SCHEMBL149279 | 0.74 | TXNRD1 (1.00) | PIM1AURKACDC25BAURKBTXNRD1 | |
| Naphthazalin SCHEMBL27700955 | 0.74 | TXNRD1 (1.00) | PIM1AURKACDC25BAURKBTXNRD1 | |
| SCHEMBL19807196 | 0.73 | PIM1 (0.69) | PIM1AURKACDC25BAURKBTXNRD1 | |
| SCHEMBL19798278 | 0.73 | PIM1 (0.73) | PIM1AURKACDC25BAURKBTXNRD1 | |
| Naphthazalin SCHEMBL6122890 | 0.72 | TXNRD1 (0.94) | PIM1AURKACDC25BAURKBTXNRD1 | |
| Naphthazalin SCHEMBL21403377 | 0.72 | TXNRD1 (0.94) | PIM1AURKACDC25BAURKBTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489623-A | APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE | THE DOW CHEMICAL COMPANY (US) | 1996-02-06 | — | — | US | claimed |
| EP-0676062-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1995-10-11 | — | — | EP | claimed |
| US-5426164-A | Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization | THE DOW CHEMICAL COMPANY (US) | 1995-06-20 | — | — | US | claimed |
| WO-1994015258-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1994-07-07 | — | — | WO | claimed |
| US-5489623-A | APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE | THE DOW CHEMICAL COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| EP-0676062-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5426164-A | Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization | THE DOW CHEMICAL COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| WO-1994015258-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1994-07-07 | — | — | WO | disclosed |