Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL28230378 | 0.84 | — | — | |
| Tetrahydrofuran SCHEMBL8896085 | 0.82 | ALDH1A1 (0.67) | TTRALDH1A1TSHRLMNACYP2E1 | |
| Oxirane SCHEMBL28403505 | 0.78 | — | — | |
| SCHEMBL3137753 | 0.78 | TTR (1.00) | TTRALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL78595 | 0.78 | TTR (1.00) | TTRALDH1A1TSHRLMNAMEN1 | |
| Dioxane SCHEMBL9836999 | 0.78 | — | — | |
| SCHEMBL16041435 | 0.78 | TTR (1.00) | TTRALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL1119 | 0.78 | TTR (1.00) | TTRALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL3137720 | 0.78 | TTR (1.00) | TTRALDH1A1TSHRLMNAMEN1 | |
| Dioxane SCHEMBL9698192 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116218119-B | Flame-retardant solid surface material and preparation method thereof | 广东热浪新材料科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116218119-A | Flame-retardant solid surface material and preparation method thereof | 广东热浪新材料科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-113912348-B | High-performance recycled concrete and preparation method thereof | 佛山市顺德区和乐商品混凝土有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-113912348-A | High-performance recycled concrete and preparation method thereof | 佛山市顺德区和乐商品混凝土有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-10428019-B2 | Chiral auxiliaries | WAVE LIFE SCIENCES LTD. (SG) | 2019-10-01 | — | — | US | disclosed |
| CN-102489276-B | Benzyl nitrogen bridged calix[2]arene[2]triazine bonded silica stationary phase, its preparation method and its purpose | UNIV ZHENGZHOU | 2013-08-21 | — | — | CN | disclosed |
| US-20130178612-A1 | CHIRAL AUXILIARIES | CHIRALGEN, LTD. (JP) | 2013-07-11 | — | — | US | disclosed |
| CN-102489275-B | Phenylalanine-substituted calix [4] arene bonded silica gel stationary phase, preparation method thereof, and application thereof | UNIV ZHENGZHOU | 2013-07-10 | — | — | CN | disclosed |
| EP-2512245-A1 | PYRIDOQUINAZOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | Merck Sharp & Dohme Corp. (US) | 2012-10-24 | — | — | EP | disclosed |
| CN-102489275-A | Phenylalanine-substituted calix [4] arene bonded silica gel stationary phase, preparation method thereof, and application thereof | UNIV ZHENGZHOU | 2012-06-13 | — | — | CN | disclosed |
| WO-2011075371-A1 | PYRIDOQUINAZOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2011-06-23 | — | — | WO | disclosed |
| US-6835745-B2 | Treating or inhibiting osteoporosis or bone demineralization, inflammatory bowel disease, prostatic hypertrophy, uterine leiomyomas, breast cancer, endometriosis, endometrial cardiovascular disease, Alzheimer's disease | WYETH | 2004-12-28 | — | — | US | disclosed |
| US-20030199570-A1 | Phenyl substituted thiophenes as estrogenic agents | WYETH | 2003-10-23 | — | — | US | disclosed |
| EP-0579169-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5563253-A | NON-RADIOACTIVE LABELLING | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-10-08 | — | — | US | disclosed |
| US-5541306-A | LABELS | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-07-30 | — | — | US | disclosed |
| US-5536821-A | Aminoalkylphosphorothioamidate oligonucleotide deratives | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1996-07-16 | — | — | US | disclosed |
| US-5321131-A | Diagnosis, therapy | HYBRIDON, INC. (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0579169-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |
| WO-1991013902-A2 | SITE-SPECIFIC FUNCTIONALIZATION OF OLIGODEOXYNUCLEOTIDES FOR NON-RADIOACTIVE LABELLING | WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY (US) | 1991-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178612-A1 | CHIRAL AUXILIARIES | POLL, PCNA, POLM | TTR 684/4885ALDH1A1 3045/4885TSHR 2617/4885 |
| US-10428019-B2 | Chiral auxiliaries | PCNA, POLL, TYMP | TTR 1146/4885ALDH1A1 2263/4885TSHR 2863/4885 |
| US-20030199570-A1 | Phenyl substituted thiophenes as estrogenic agents | ESR2, ESR1, GPER1 | TTR 3375/4885ALDH1A1 1071/4885TSHR 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.