Tetrahydrofuran

Tetrahydrofuran

SCHEMBL8896085

C1CCOC1.ClC(Cl)(Cl)Cl

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
TSHR P16473 2/20 0.39
TTR P02766 1/20 0.39
LMNA P02545 1/20 0.33
CYP2E1 P05181 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL29225232 0.87
Tetrahydrofuran SCHEMBL27896308 0.85 ALDH1A1 (0.57) ALDH1A1TSHRTTR
Tetrahydrofuran SCHEMBL28140707 0.85 ALDH1A1 (0.57) ALDH1A1TSHRTTR
Tetrahydrofuran SCHEMBL28049846 0.83
Chloromethane SCHEMBL27584162 0.83
Dioxane SCHEMBL1980951 0.82 TTR (0.60) ALDH1A1TSHRTTRLMNACYP2E1
SCHEMBL30466481 0.82 ALDH1A1 (1.00) ALDH1A1TSHRTTR
SCHEMBL9576477 0.82 ALDH1A1 (1.00) ALDH1A1TSHRTTR
Tetrahydrofuran SCHEMBL130914 0.82
SCHEMBL30432886 0.82 ALDH1A1 (1.00) ALDH1A1TSHRTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117529365-A Epoxidation catalyst system and process for preparing epoxide 科思创德国股份有限公司 2024-02-06 CN disclosed
CN-105683326-B Hot-melt adhesive composition 株式会社可乐丽 2018-09-25 CN disclosed
CN-105473629-B Star-shaped vinyl ether polymer 丸善石油化学株式会社 2018-06-01 CN disclosed
CN-107531980-A Acrylic thermoplastic's polymer composition is used in stacking 株式会社可乐丽 2018-01-02 CN disclosed
CN-103889951-B Azole derivative 大正制药株式会社 2016-12-14 CN disclosed
CN-101252991-B Peroxide decomposition catalyst SUMITOMO CO LTD 2012-10-03 CN disclosed
CN-101252991-A Peroxide decomposition catalyst SUMITOMO CHEMICAL COMPANY LIMT (JP) 2008-08-27 CN disclosed
WO-1997021678-A1 CARBAMIC ACID DERIVATIVES AS LEUKOTRIENE ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 1997-06-19 WO disclosed
US-4282390-A PARASITICIDES ICI AUSTRALIA LIMITED (AU) 1981-08-04 US disclosed
US-4163801-A PARASITICIDES, NEMATOCIDES ICI AUSTRALIA LIMITED (AU) 1979-08-07 US disclosed