Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200210 | 0.83 | HTR2A (0.33) | CYP4F2CYP4A11HPGDSHTT | |
| SCHEMBL198147 | 0.81 | CYP4F2 (0.38) | CYP4F2CYP4A11HPGDSF2POLB | |
| SCHEMBL2808309 | 0.81 | CYP4F2 (0.38) | CYP4F2CYP4A11HPGDSF2POLB | |
| SCHEMBL14856639 | 0.78 | VNN1 (0.37) | — | |
| SCHEMBL14856727 | 0.77 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL14856657 | 0.77 | KDM4E (0.45) | CYP4F2CYP4A11POLB | |
| SCHEMBL184727 | 0.77 | HDAC3 (0.39) | — | |
| SCHEMBL2787463 | 0.76 | VNN1 (0.38) | — | |
| SCHEMBL185596 | 0.76 | VNN1 (0.38) | — | |
| SCHEMBL185855 | 0.76 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |